Publications
- Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation.
 2025 | PubMed PubMed
- Identification of a robust promoter in mouse and human hepatocytes by in vivo biopanning of a barcoded AAV library.
 2025 | PubMed PubMed
- AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion.
 2025 | PubMed PubMed
- Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers.
 2025 | PubMed PubMed
- Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system.
 2024 | PubMed PubMed
- Human Hepatocytes Can Give Rise to Intrahepatic Cholangiocarcinomas.
 2024 | PubMed PubMed
- Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages.
 2023 | PubMed PubMed
- Human iPSC-Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System.
 2023 | PubMed PubMed
- Reply.
 2022 | PubMed PubMed
- Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency.
 2021 | PubMed PubMed
- Integrated Isogenic Human Induced Pluripotent Stem Cell-Based Liver and Heart Microphysiological Systems Predict Unsafe Drug-Drug Interaction.
 2021 | PubMed PubMed
- Induced Pluripotent Stem Cell-derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile.
 2021 | PubMed PubMed
- Emerging cell therapy for biliary diseases.
 2021 | PubMed PubMed
- Transcriptomic Traces of Adult Human Liver Progenitor Cells.
 2020 | PubMed PubMed
- Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration.
 2019 | PubMed PubMed
- Hepatocyte Nuclear Factor 4 Alpha Activation Is Essential for Termination of Liver Regeneration in Mice.
 2019 | PubMed PubMed
- De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation.
 2018 | PubMed PubMed
- Postnatal Organogenesis by Transdifferentiation.
 2018 | Postnatal Organogenesis by Transdifferentiation.
 ' href="https://researcherprofiles.org/profile/117442260">UCSF Research Profile
- Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference.
 2016 | PubMed PubMed
- In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis.
 2016 | PubMed PubMed
- Assessing the therapeutic potential of lab-made hepatocytes.
 2016 | PubMed PubMed
- Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha.
 2016 | PubMed PubMed
- A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.
 2014 | PubMed PubMed
- AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites.
 2014 | PubMed PubMed
- Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury.
 2014 | Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury.
 ' href="https://researcherprofiles.org/profile/79294168">UCSF Research Profile
- Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury.
 2014 | PubMed PubMed
- Brief report: Parthenogenetic embryonic stem cells are an effective cell source for therapeutic liver repopulation.
 2014 | PubMed PubMed
- Failure to achieve normal metabolic response in non-obese diabetic mice and streptozotocin-induced diabetic mice after transplantation of primary murine hepatocytes electroporated with the human proinsulin gene (p3MTChins).
 2014 | PubMed PubMed
- Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia.
 2014 | PubMed PubMed
- Mouse liver repopulation with hepatocytes generated from human fibroblasts.
 2014 | PubMed PubMed
- Addendum: A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice.
 2014 | PubMed PubMed
- Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development.
 2013 | PubMed PubMed
- MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer.
 2013 | PubMed PubMed
- Transplantable liver organoids made from only three ingredients.
 2013 | PubMed PubMed
- Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells.
 2013 | PubMed PubMed
- A therapy for liver failure found in the JNK yard.
 2013 | PubMed PubMed
- Akt/Notch activation drives rapid cholangiocarcinoma development originating from mature hepatocytes in the mouse.
 2013 | Akt/Notch activation drives rapid cholangiocarcinoma development originating from mature hepatocytes in the mouse.
 ' href="https://researcherprofiles.org/profile/79296128">UCSF Research Profile
- Cholangiocarcinomas can originate from hepatocytes in mice.
 2012 | PubMed PubMed
- A ZFN/piggyBac step closer to autologous liver cell therapy.
 2012 | PubMed PubMed
- A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration.
 2012 | PubMed PubMed
- Stem cells in liver diseases and cancer: recent advances on the path to new therapies.
 2012 | PubMed PubMed
- Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.
 2011 | PubMed PubMed
- A simple code for installing hepatocyte function.
 2011 | PubMed PubMed
- Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration.
 2011 | PubMed PubMed
- Core promoter recognition complex changes accompany liver development.
 2011 | PubMed PubMed
- The MAP3K TAK1: a chock block to liver cancer formation.
 2010 | PubMed PubMed
- Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice.
 2010 | PubMed PubMed
- Transplanted nonviable human hepatocytes produce appreciable serum albumin levels in mice.
 2010 | PubMed PubMed
- miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues.
 2010 | PubMed PubMed
- Therapeutic liver reconstitution with murine cells isolated long after death.
 2010 | PubMed PubMed
- MicroRNAs control hepatocyte proliferation during liver regeneration.
 2010 | PubMed PubMed
- Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis.
 2008 | PubMed PubMed
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 2008 | ????????in vitro???.
 ' href="https://researcherprofiles.org/profile/79293899">UCSF Research Profile
- A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice.
 2008 | PubMed PubMed
- On the origin of the term "stem cell".
 2007 | PubMed PubMed
- Myeloid lineage progenitors give rise to vascular endothelium.
 2006 | PubMed PubMed
- Bone marrow-derived cells fuse with normal and transformed intestinal stem cells.
 2006 | PubMed PubMed
- Sustained phosphorylation of Bid is a marker for resistance to Fas-induced apoptosis during chronic liver diseases.
 2006 | PubMed PubMed
- Myeloid Lineage-Restricted Progenitors Contribute to Vascular Endothelium.
 2005 | Myeloid Lineage-Restricted Progenitors Contribute to Vascular Endothelium.
 ' href="https://researcherprofiles.org/profile/117442138">UCSF Research Profile
- In vivo genetic selection of renal proximal tubules.
 2005 | PubMed PubMed
- Therapeutic cell fusion.
 2005 | PubMed PubMed
- Delineating the hepatocyte's hematopoietic fusion partner.
 2004 | PubMed PubMed
- Myelomonocytic cells are sufficient for therapeutic cell fusion in liver.
 2004 | PubMed PubMed
- Embryonic versus adult stem cell pluripotency: in liver only fusion matters.
 2003 | PubMed PubMed
- Cell fusion is the principal source of bone-marrow-derived hepatocytes.
 2003 | PubMed PubMed
- Argininosuccinate lyase (ASL) deficiency: mutation analysis in 27 patients and a completed structure of the human ASL gene.
 2002 | PubMed PubMed
- Genomic structure and transcript variants of the human methylenetetrahydrofolate reductase gene.
 2000 | PubMed PubMed
- Telomerase activity distinguishes between neuroblastomas with good and poor prognosis.
 1999 | PubMed PubMed
- Telomerase activity in human proliferative breast lesions.
 1998 | PubMed PubMed
- Nonisotopic single strand conformation analysis of the 5 alpha-reductase type 2 gene for the diagnosis of 5 alpha-reductase deficiency.
 1996 | PubMed PubMed
- Molecular genetic analysis and human chorionic gonadotropin stimulation tests in the diagnosis of prepubertal patients with partial 5 alpha-reductase deficiency.
 1996 | PubMed PubMed
