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Willenbring Lab »  Lab Members »  Postdoctoral Fellows »  Feng Chen, Ph.D.
Feng Chen, Ph.D.

Feng Chen, Ph.D.

  • Postdoctoral Fellow

Contact Information

(415) 476-2420
[email protected]
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Stanford University, Stanford, CA, Ph.D., Genetics, 2013

Harvard University, Cambridge, MA, A.B., Biochemical Sciences, 2006

  • Cell and molecular mechanisms of liver regeneration
  • Growing liver tissue from induced pluripotent stem cells

Feng Chen, Ph.D. is a postdoctoral fellow in the laboratory of Dr. Holger Willenbring. She is a former UCSF Liver Center trainee, and is currently supported by a fellowship from the Jane Coffin Childs Memorial Fund.

She has a long-standing interest in tissue regeneration and is currently examining how the mammalian liver regenerates. She is developing tools and techniques to better trace the fate of liver cells in mice, and to dissect the molecular mechanisms that regulate liver regeneration. Prior to joining the Willenbring Lab, Feng completed her graduate studies at Stanford University in the laboratory of Dr. Mark Krasnow, where she studied progenitor cells in the Drosophila melanogaster trachea. She found a novel mechanism where progenitor cells giving rise to new trachea grow out of their niche by migrating along and following a chemoattractant cue expressed by older, decaying, tracheal tissue, a mechanism that may be present in other contexts of tissue regeneration.

Feng is also interested in growing liver tissue from induced pluripotent stem cells for transplantation into a mouse model of bile duct insufficiency.

  Confired By    
  • Postdoctoral Fellowship
  • Jane Coffin Childs Memorial Fund
  • 2015 - 2018
  • NIDDK T32 Hepatology training grant
  • UCSF Liver Center
  • 2014 - 2015
  • Data provided by UCSF Profiles, powered by CTSI
    1. Chen F, Jimenez RJ, Sharma K, Luu HY, Hsu BY, Ravindranathan A, Stohr BA, Willenbring H. Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration. Cell Stem Cell. 2020 01 02; 26(1):27-33.e4. View in PubMed
    2. Shaw LM, Lyu B, Turner R, Li C, Chen F, Han X, Fu D, Dubcovsky J. FLOWERING LOCUS T2 regulates spike development and fertility in temperate cereals. J Exp Bot. 2019 Jan 01; 70(1):193-204. View in PubMed
    3. Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. 2018 05; 557(7704):247-251. View in PubMed
    4. Progenitor outgrowth from the niche in Drosophila trachea is guided by FGF from decaying branches. Science. 2014 Jan 10; 343(6167):186-9. View in PubMed
    5. Chen F, Nonogaki H, Bradford KJ. A gibberellin-regulated xyloglucan endotransglycosylase gene is expressed in the endosperm cap during tomato seed germination. J Exp Bot. 2002 Feb; 53(367):215-23. View in PubMed
    1. "Development of a screen to identify factors that mediate the transdifferentiation of hepatocytes to cholangiocytes," 2015, Poster presentation, USC/UCSF/UCLA Stem Cell Retreat, Santa Barbara, CA.


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